Human TM2 domain-containing protein 1 (TM2D1) ELISA Kit
1063.5 EUR
1063.5 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 749 - KTE60312-96T
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 96T
Parameters
| Additional information | TM2D1 is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death.BBP bound the 42-amino acid form of human beta-amyloid peptide in vitro with high affinity and specificity. Expression of a signaling-deficient dominant-negative BBP mutant suppressed sensitivity of human Ntera-2 neurons to beta-amyloid-mediated toxicity. |
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| Storage and shipping | Storage: The unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.Shipping:Gel pack with blue ice. |
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