Human PD-1 Jurkat Cell Line
2007.38 €
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Catalog number: 426 - E24C00017
Product Category: Business & Industrial > Science & Laboratory
Gentaur
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60535
PD-1 / NFAT Reporter - Jurkat Cell Line
Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human PD-1 (Programmed Cell Death 1, PDCD1, SLEB2, CD279, GenBank Accession #NM_005018)._x000D_
17384.63 €
ABC-RC0117
Human PD-1 / NFAT Reporter Cell Line- Jurkat
Human PD-1 / NFAT Reporter Cell Line is derived from Jurkat. Application: • Screen for activators or inhibitors of PD-1 signaling in a cellular context • Characterize the biological activity of PD-1 and its interactions with ligands
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78384
NFAT Reporter (eGFP) Jurkat Recombinant Cell Line
Recombinant Jurkat T-cells expressing an enhanced GFP (eGFP) gene under the control of NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway can be monitored by examining eGFP expression.
3545.10 €
78525
GR-GAL4 Luciferase Reporter Jurkat Cell Line
The Glucocorticoid Receptor (GR)-GAL4 Luciferase Reporter Jurkat Cell Line contains an engineered transcription factor stably integrated into the genome of Jurkat cells, which consists of the glucocorticoid receptor ligand binding domain fused to the DNA binding domain of GAL4. This fusion construct activates firefly luciferase expression which is under the control of a multimerized GAL4 upstream activation sequence (UAS). This allows for specific detection of glucocorticoid-induced activation of the glucocorticoid receptor without the need for individual transcriptional targets and with low cross-reactivity for other nuclear receptor pathways. This cell line is validated for response to stimulation of dexamethasone and to the treatment with mifepristone, an inhibitor of the glucocorticoid signaling pathway.
3598.13 €
78662
NFAT Luciferase-eGFP Reporter Jurkat Cell Line
Recombinant Jurkat T cells expressing both firefly luciferase and enhanced GFP (eGFP) under the control of NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway can be monitored by examining either firefly luciferase or eGFP expression.