IHUMSIL21RAFLY2UG

Human, Mouse IL-21 Recombinant Protein (Animal Free) Lyophilized

Human, Mouse IL-21 Recombinant Protein (Animal Free) Lyophilized

696.39 €

MBS8432859-INQUIRE

Human, Mouse IL-21 Recombinant Protein (Animal Free) Lyophilized

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40-732

IL-21 Recombinant Protein (Animal Free)

IL-21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL-21 include: inducing the differentiation of T cell-stimulated B cells into plasma cells and memory B cells; the stimulation of IgG production in conjunction with IL-4; and the induction of apoptotic effects in naïve B cells and stimulated B cells in the absence of T cell signaling. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 exerts its effect through binding to a specific type I cytokine receptor, IL-21R, which also contains the γ chain (γc) found in other cytokine receptors, including IL-2, IL-4, IL-7, IL-9 and IL-15. The IL-21/IL-21R interaction triggers a cascade of events, which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant Human IL-21 is a 15.4 kDa protein consisting of 132 amino acid residues.

621.71 €

IRTMSEGFRAFLY20UG

Rat, Mouse EGF Recombinant Protein (Animal Free) Lyophilized

Rat, Mouse EGF Recombinant Protein (Animal Free) Lyophilized

696.39 €

IHUMSBAFFRAFLY5UG

Human, Mouse BAFF Recombinant Protein (Animal Free) Lyophilized

Human, Mouse BAFF Recombinant Protein (Animal Free) Lyophilized

696.39 €

IHUMSEGFRAFLY100UG

Human, Mouse EGF Recombinant Protein (Animal Free) Lyophilized

Human, Mouse EGF Recombinant Protein (Animal Free) Lyophilized

696.39 €