Catalog number: 109 - IHUHER2ERBB2498648RHISLY100UG
Product Category: Business & Industrial > Science & Laboratory
Size: each
IHUHER2ERBB2498648RHISLY100UG
Human Her2 / ErbB2 (498-648) Recombinant Protein His Tag Lyophilized
HE2-H52H4
Human Her2 (498-648), His Tag (HE2-H52H4) is expressed from human 293 cells (HEK293). It contains AA Asn 498 - Ala 648 (Accession # P04626-1).
11-225
Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2, HER-2,HER-2 /neu, NEU, NGL,TKR1 and c-erb B2,and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family, more commonly known as the epidermal growth factor receptor family. HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. HER2 is thought to be an orphan receptor, with none of the EGF family of ligands able to activate it. Approximately 30% of breast cancers have an amplification of the HER2 gene or overexpression of its protein product. Overexpression of this receptor in breast cancer is associated with increased disease recurrence and worse prognosis. HER2 appears to play roles in development, cancer, communication at the neuromuscular junction and regulation of cell growth and differentiation .
HE2-C52Hb
Cynomolgus Her2, His Tag (HE2-C52Hb) is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Thr 652 (Accession # XP_005584091.2).
HE2-H5225
Human Her2, His Tag (HE2-H5225) is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Thr 652 (Accession # P04626-1).
HE2-H5225-100ug
Human Her2, His Tag (HE2-H5225) is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Thr 652 (Accession # P04626-1).