Human BAFF-R Protein, hFc Tag
573.88 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 544 - MBS8575157-001mg
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 0.01mg
Z100015
Recombinant Human BAFF-R (TNFRSF13C)
The B cell-activating factor from the TNF family (BAFF), is emerging as an important regulator of B cell and T cell responses. BAFF was originally identified as a factor responsible for B cell survival and maturation. BAFF binds to several receptors. These include transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI), BAFF-R (BR3), and B cell maturation Ag (BCMA). BAFF-R appears to be particularly important for the regulation of B cell survival and maturation in the spleen, because A/WySnJ mice expressing a defective BAFF-R have disrupted B cell maturation, similar to that seen in BAFF-deficient mice.