70R-HR003

Hepatitis E Virus antibody

Affinity purified Rabbit polyclonal Hepatitis E Virus antibody

668.12 €

MBS534669-01mg

Hepatitis E Virus antibody

843.60 €

MBS534669-5x01mg

Hepatitis E Virus antibody

2949.08 €

NCP0149

Chikungunya virus E protein ectodomain（CHIKV-E）

Chikungunya virus (CHIKV) belongs to the Semliki Forest antigenic group of the genus Alphaviridae, which includes other arthritogenic alphaviruses, such as o’nyong-nyong, Ross River, Barmah Forest, and Mayaro viruses.Its genome is closely related to that of o’nyong-nyong virus, and consists of a single 11.8-kbp strand of positive sense RNA, which encodes a 2472 amino acid nonstructural and a 1244 amino acid structural polyprotein.3 The polyproteins give rise to the four nonstructural proteins (nsP1-4) that make up the viral replication machine, and five structural proteins. Each spherical viral particle is approximately 70 nm in diameter and is comprised of a strand of genomic RNA, encapsidated by capsid (C) proteins, surrounded by a host cell–derived lipid bilayer spiked with heterodimers of envelope proteins E1 and E2.4 The other two structural proteins, 6K and E3, are leader peptides for E1 and E2, respectively, and are not observed in abundance in the mature virion.

401.98 €

NCP0141

West Nile virus E protein ectodomain（WNV-E）

West Nile (WN) virus is a mosquito-borne flavivirus and human, equine, and avian neuropathogen. The virus is indigenous to Africa, Asia, Europe, and Australia, and has recently caused large epidemics in Romania, Russia, and Israel. Birds are the natural reservoir (amplifying) hosts, and WN virus is maintained in nature in a mosquito-bird-mosquito transmission cycle primarily involving Culex sp mosquitoes. WN virus was recently introduced to North America, where it was first detected in 1999 during an epidemic of meningoencephalitis in New York City. During 1999-2002, the virus extended its range throughout much of the eastern parts of the USA, and its range within the western hemisphere is expected to continue to expand. During 1999-2001, 142 cases of neuroinvasive WN viral disease of the central nervous system (including 18 fatalities), and seven cases of uncomplicated WN fever were reported in the USA. Most human WN viral infections are subclinical but clinical infections can range in severity from uncomplicated WN fever to fatal meningoencephalitis; the incidence of severe neuroinvasive disease and death increase with age. Serology remains the mainstay of laboratory diagnosis.

401.98 €

NCP0143

Japanese encephalitis virus E protein ectodomain（JEV-E）

Japanese encephalitis virus (JEV) is the most important cause of epidemic encephalitis worldwide, with an estimated 35,000 to 50,000 cases and 10,000 deaths annually. The virus is a member of the JE serogroup of the genus Flavivirus, family Flaviviridae, and is transmitted between vertebrate hosts by mosquitoes, principally by Culex tritaeniorhynchus. Other important members of the same serogroup of flaviviruses include West Nile virus (WNV), which has recently spread to cause outbreaks of encephalitis in North America, St. Louis encephalitis virus (SLEV), Kunjin virus (KUNV), and Murray Valley encephalitis virus (MVEV). Like other flaviviruses, JEV consists of a small (50 nm) glycoprotein-containing lipid envelope surrounding a nucleocapsid which encloses one molecule of single-stranded positive-sense RNA. This 11-kb molecule comprises 5- and 3-untranslated regions (UTRs), between which lie a single open reading frame carrying genes for three structural proteins (capsid [C], premembrane [PrM], and envelope [E]) and seven nonstructural (NS) proteins

401.98 €