Genorise® Recombinant Equine GDF-8 protein
859.5 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 10328 - GR104309
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 5 µg
91-625
GDF-8 Recombinant Protein
Mouse Growth/differentiation factor 8(Mstn, GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer, and interacts with WFIKKN2, leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues. Experiments in mice have improved that GDF-8 is a key regulator of mesenchymal stem cell proliferation and differentiation, and mice lacking Myostatin encoding gene show decreased body fat and a generalized increase in bone density and strength.
1362.1 €