GABAA R Delta Polyclonal Antibody
480.00 €
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Catalog number: 965 - JOT-AP03431-100ul
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 100ul
BT-AP03431-100ul
GABAA R Delta Polyclonal Antibody
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. GABRD encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.
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