Dra I-HC unit: 3500, High Concentration
Ask for quotation
On request
quantity
product details
Catalog number: 377 - YRDRA1-HC
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 1 vial
354262
CORNING® MATRIGEL® MATRIX HIGH CONCENTRATION (HC), PHENOL-RED FREE *LDEV-FREE, 10ML
Advanced Cells - DL; ECM - DL
1535.00 €
354263
CORNING® MATRIGEL® MATRIX HIGH CONCENTRATION (HC), GROWTH FACTOR REDUCED *LDEV-FREE, 10ML
Advanced Cells - DL; ECM - DL
1522.27 €
K146
saCas9 Null Mutant Protein (High Concentration)
The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 system is the latest RNA-guided, endonuclease tool in genome editing which allows for very specific genomic disruption and replacement. ;;The saCas9 Null Mutant Protein is created by mutating both cleavage domains of the wild type saCas9. Such a saCas9 protein retains its ability to bind to genomic DNA through sgRNA:genomic DNA base pairing, however, the saCas9 Null Mutant does not induce cleavage. Therefore, this protein can provide a useful negative control for CRISPR experiments. In addition, binding of the Null Mutant can act as a roadblock to hinder transcription, thus offering a useful tool to achieve reversible knock-down of gene expression.;;The Cas9 nuclease from the bacteria <i>Staphylococcus aureus</i>, abbreviated saCas9, is gaining popularity as an alternative to spCas9 due to its relatively smaller size. The saCas9 PAM sequence is 5’-NNGRRN (preferably 5’-NNGRRT).