dCas9-Null Lentivirus
820.63 €
In Stock
quantity
product details
Catalog number: 500 - LVP1597
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 1x10^8 IFU/ml x 200ul
LVP1597
dCas9-Null Lentivirus
Pre-made control lentivirus express dCas9-Null fusion, do not contain any antibiotic selection.
820.63 €
LVP1594
dCas9-Null (Puro) Lentivirus
Pre-made control lentivirus express dCas9-Null fusion, containing Puromycin selection.
820.63 €
LVP1595
dCas9-Null (Bsd) Lentivirus
Pre-made control lentivirus express dCas9-Null fusion, containing Blasticidin selection.
820.63 €
78011-1
TMPRSS2 Lentivirus
Human transmembrane serine protease 2 (TMPRSS2) is an enzyme primarily expressed by endothelial cells across the respiratory and digestive tracts. It is involved in viral entry and spread of coronaviruses including SARS-CoV-2, the virus that causes COVID19. TMPRSS2 primes the spike protein by cleaving at the S1/S2 site, leading to the virus fusing to the respiratory epithelia on the cell surface through binding to ACE2. Blocking TMPRSS2 activity could potentially be an effective clinical therapy for COVID-19._x000D_<br />The TMPRSS2 Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an TMPRSS2 gene (NM_005656.4) driven by an EF1a promoter._x000D_