Cynomolgus MERTK / Mer Protein, Fc Tag (MALS verified)
3078.6 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 716 - MEK-C5253
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 100ug
Parameters
| Additional information | Tyrosine-protein kinase Mer(MERTK) is a member of the TYRO3/AXL/MER (TAM) receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3. |
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| Storage and shipping | -20℃ RT |
MEK-C5253
Cynomolgus MERTK / Mer Protein, Fc Tag (MALS verified)
Cynomolgus MERTK, Fc Tag (MEK-C5253) is expressed from human 293 cells (HEK293). It contains AA Ala 23- Ile 507 (Accession # XP_005575320.1).
3078.6 €
IL4-C5259
Cynomolgus IL-4 Protein, Fc Tag (MALS verified)
Cynomolgus IL-4, Fc Tag (IL4-C5259) is expressed from human 293 cells (HEK293). It contains AA His 25 - Ser 153 (Accession # P79339-1).
3562.56 €
NE4-C5253
Cynomolgus Nectin-4 Protein, Fc Tag (MALS verified)
Cynomolgus Nectin-4 Protein, Fc Tag (NE4-C5253) is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Ser 349 (Accession # XP_005541277.1).
658.8 €
SIA-C52H7
Cynomolgus SIRP alpha / CD172a Protein, His Tag (MALS verified)
Cynomolgus SIRP alpha, His Tag (SIA-C52H7) is expressed from human 293 cells (HEK293). It contains AA Glu 31 - Asn 370 (Accession # NP_001271679.1).
3078.6 €
CD9-C5PH3
Cynomolgus CD39 Protein, His Tag (active enzyme, MALS verified)
Cynomolgus CD39 Protein, His Tag (CD9-C5PH3) is expressed from CHO cells. It contains AA Thr 60 - Val 500 (Accession # XP_015311944.1).
3178.6 €
LC2-C5223
Cynomolgus Lipocalin-2 / NGAL Protein, His Tag (MALS verified)
Cynomolgus Lipocalin-2, His Tag (LC2-C5223) is expressed from human 293 cells (HEK293). It contains AA Gln 21 - Gly 198 (Accession # XP_005580845.3).
2817 €
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