CHMFL-ABL-039
1020.12 €
1020.12 €
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Catalog number: 544 - MBS5766341-10mg
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 10mg
HY-111874
SNIPER(ABL)-039
SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 nM. IC50s are 0.54 nM, 10 nM, 12 nM, and 50 nM for ABL, cIAP1, cIAP2, XIAP, respectively[1].
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HY-126143
CHMFL-ABL-039
CHMFL-ABL-039 is a type II native ABL kinase and drug-resistant V299L mutant BCR-ABL inhibitor with the IC50s of 7.9 nM and 27.9 nM, respectively. CHMFL-ABL-039 is used in the research of chronic myeloid leukemia[1].
474.09 €