MBS154578-01mg

CD80 Antibody [10A1]

822.50 €

MBS154578-5x01mg

CD80 Antibody [10A1]

3028.25 €

RF16042-002mg

CD80 Antibody [10A1]

CD80 Antibody: CD80, also known as B7-1, is a type I membrane protein that is a member of the immunoglobulin superfamily. Like the related protein CD86, this protein is expressed by antigen-presenting cells, and is the ligand for two proteins at the cell surface of T cells, CD28 and the cytotoxic T-lymphocyte-associated protein 4 (CTLA-4). Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell and induces T-cell proliferation and cytokine production. CTLA-4 binding negatively regulates T-cell activation and diminishes the immune response (1). Blocking the CTLA-4-CD80/CD86 interaction has been shown to enhance T-cell functions in acute lymphoblastomic leukemia (ALL), suggesting that this pathway may be an attractive target for future cancer immunotherapy (2).

474.55 €

E-AB-F0992UE-100ug

APC Anti-Mouse CD80 Antibody[16-10A1]

FCM

12038.00 €

E-AB-F0992UE-25ug

APC Anti-Mouse CD80 Antibody[16-10A1]

FCM

6818.00 €

E-AB-F0992UE-each

APC Anti-Mouse CD80 Antibody[16-10A1]

FCM

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