![CD40:CD40L[Biotinylated] Inhibitor Screening Assay Kit](/images/no-image-product-box.jpg "CD40:CD40L[Biotinylated] Inhibitor Screening Assay Kit")
CD40:CD40L[Biotinylated] Inhibitor Screening Assay Kit
1367.5 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 421 - 79257
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 96 rxns.
Parameters
| Additional information | Applications: This kit is useful for screening for inhibitors of CD40L binding to CD40.; |
|---|---|
| Storage and shipping | Shipping conditions: -80°C; Storage conditions: Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.; |
| Storage and shipping | With |
78590
CD137:CD137L[Biotinylated] Inhibitor Screening Assay Kit
The CD137:CD137L [Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of CD137:CD137L interaction. The assay takes advantage of the highly sensitive detection of biotin-labeled CD137L by streptavidin-HRP. First, CD137 is coated on a 96-well plate. Next, CD137L-biotin is incubated with CD137. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.Need us to run inhibitor screens or profile your compounds against CD137:CD137L[Biotinylated]? Check out ourImmunotherapy Biochemical Screening Services.
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72025
CD137[Biotinylated]:CD137L Inhibitor Screening Assay Kit
The CD137:CD137L Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of CD137:CD137L interaction. The key to this kit is the high sensitivity of detection of biotin-labeled CD137 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, CD137L is coated on a 96-well plate. Next, CD137-biotin is incubated with CD137L on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.
1845 €
EP-121
CD27L [Biotinylated] : CD27 Inhibitor Screening ELISA Kit
Cluster of Differentiation 70 (CD70) is also known as CD27 ligand (CD27L / CD27LG), TNFSF7, TNFSF7G, is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and is a surface antigen found on activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its receptor CD27 induces in priming, effector functions, differentiation and memory formation of T-cells, and thus is invloved in the biological processes including T-cell activation, the proliferation of costimulated T-cells, as well as the generation of cytolytic T-cells. CD70 on T cells provides costimulatory signals that are required for T cell proliferation, clonal expansion and the promotion of effector T cell formation. CD70 on mouse B cell has been shown to inhibit terminal differentiation of activated B cells into plasma cells and enhances commitment to memory B cell responses. CD70 induces proliferation and IFNγ production, on NK cells.
1064.28 €
EP-131
TIGIT : CD155 [Biotinylated] Inhibitor Screening ELISA Kit
CD155 and ITIM domains (TIGIT) is a novel type of immune checkpoint. CD155 is an adhesion molecule that is upregulated during tumor progression and promotes the proliferative and migratory abilities of tumor cells via various pathways. TIGIT, an inhibitory receptor, is mainly expressed on natural killer (NK), CD8+ T, CD4+ T and T regulatory (Treg) cells. CD155 transmits immune signals via interacting with the inhibitory checkpoint receptor TIGIT, thereby inhibiting the function of T and NK cells.CD155 is highly expressed on the surface of DC cells. When TIGIT on T cells binds to CD155 on DC cells, CD155 will send signals to DC cells to up-regulate the secretion of IL-10 and down-regulate the secretion of IL-12, thereby weakening the immune response mediated by DC cells. DC cells are important antigen-presenting cells in the body, and reduced DC cell activity in turn reduces T cell activity.
1064.28 €
EP-131-96tests
TIGIT : CD155 [Biotinylated] Inhibitor Screening ELISA Kit
CD155 and ITIM domains (TIGIT) is a novel type of immune checkpoint. CD155 is an adhesion molecule that is upregulated during tumor progression and promotes the proliferative and migratory abilities of tumor cells via various pathways. TIGIT, an inhibitory receptor, is mainly expressed on natural killer (NK), CD8+ T, CD4+ T and T regulatory (Treg) cells. CD155 transmits immune signals via interacting with the inhibitory checkpoint receptor TIGIT, thereby inhibiting the function of T and NK cells.CD155 is highly expressed on the surface of DC cells. When TIGIT on T cells binds to CD155 on DC cells, CD155 will send signals to DC cells to up-regulate the secretion of IL-10 and down-regulate the secretion of IL-12, thereby weakening the immune response mediated by DC cells. DC cells are important antigen-presenting cells in the body, and reduced DC cell activity in turn reduces T cell activity.
1064.28 €
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