CD120b. TNF-RII (p75/p80), Antibody
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Catalog number: 137 - GWB-828549
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 0.1 mg
91-579
TNF RII Recombinant Protein
Tumor Necrosis Factor Receptor Superfamily Member 1B (TNFRSF1B) is a member of the Tumor Necrosis Factor Receptor Superfamily. TNFRSF1B contains four TNFR-Cys repeats. TNFRSF1B can be cleaved into the following 2 chains: Tumor necrosis factor receptor superfamily member 1b and membrane form and Tumor necrosis factor-binding protein 2. TNFRSF1B is a receptor with high affinity for TNFSF2/TNF- alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin- alpha. TNFRSF1B mediates most of the metabolic effects of TNF- alpha. TNF- alpha-induced apoptosis suggests that it regulates TNF- alpha function by antagonizing its biological activity.
1022.58 €
91-624
TNF RII Recombinant Protein
Tumor necrosis factor receptor superfamily member 1B(TNFRSF1B) is expressed by the gene TNFRSF1B. The soluble form is produced from the membrane form by proteolytic processing. It can bind to TRAF2, and interacts with BMX. It can act as the receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha.
1118.02 €