HY-143235

BRD4 Inhibitor-15

BRD4 Inhibitor-15 (compound 13) is a potent BRD4 inhibitor, with an IC50 of 18 nM. BRD4 Inhibitor-15 induces apoptosis of 22RV1 cells by regulating Bcl-2/Bax proteins and activating caspase-3 signaling pathway. BRD4 Inhibitor-15 down-regulates the c-Myc level in 22RV1 cells. BRD4 Inhibitor-15 can be used for prostate cancer research[1].

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HY-143420

ATX inhibitor 15

ATX inhibitor 15 (compound 30), a indole-based carbamate derivative, is a potent autotaxin (ATX) inhibitor with an IC50 of 2.17 nM. ATX inhibitor 15 inhibits in vivo ATX and the gene expression of pro-fibrotic factors. ATX inhibitor 15 has lung protection effects in Bleomycin challenged mice lung fibrosis model[1].

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HY-145821

Tubulin inhibitor 15

Tubulin inhibitor 15 is a potent tubulin inhibitor. Tubulin inhibitor 15 shows antiproliferative activity. Tubulin inhibitor 15 shows cytotoxicity in HepG2 cells[1].

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MBS835109-5x01mL

Protease Inhibitor 15 antibody

6181.32 €

T11769-10mg

KRAS G12C inhibitor 15

KRAS G12C inhibitor 15

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T11769-1g

KRAS G12C inhibitor 15

KRAS G12C inhibitor 15

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