APC Anti-Human CD49d Antibody[9F10]

E16FHA049d-025

APC anti-human CD49d

Available in various conjugation types.

962.5 €

E16FHA049d-100

APC anti-human CD49d

Available in various conjugation types.

1872.49 €

DL21760F-20Tests

APC Anti-Human CD49d Antibody

CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells.

517.5 €

MBS213115-02mg

MOUSE ANTI HUMAN CD49d

822.5 €

MBS213115-5x02mg

MOUSE ANTI HUMAN CD49d

2824.25 €

MBS213116-01mg

MOUSE ANTI HUMAN CD49d

637.62 €