Antitumor agent-126 (Compound II4) is a photoactive (IC50= 0.149) anticancer agent with significant near-infrared fluorescence emission at 650-760 nm. Antitumor agent-126 has antiproliferative activity and can induce apoptosis after laser irradiation. Antitumor agent-126 effectively inhibits tumor growth in mouse xenograft models exposed to 650 nm laser irradiation. Antitumor agent-126 can be used in cancer research[1].
Antibacterial agent 126 is a potent antibacterial agent. Antibacterial agent 126 reduces the burden of biofilm to avoid developing agent resistance. Antibacterial agent 126 disturbs the membrane integrity and leads to the leakage of intracellular materials. Antibacterial agent 126 increase in ROS and reactive nitrogen species (RNS) production[1].