Anti-TLR6 (2B10)
811.43 €
In Stock
quantity
product details
Catalog number: 10006 - YF-MA17258
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 100 ug
70R-2269
TLR6 antibody
Rabbit polyclonal TLR6 antibody raised against the middle region of TLR6
928.70 €
3651-002mg
TLR6 Antibody
TLR6 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR6 was first identified as a close homolog of TLR1, sharing 69% sequence identify. Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall particle zymosan. Activation of these complexes not only initiates pro-inflammatory cascades, but also can lead to apoptotic responses.