Anti Human PAI-1 antiserum

102-P246

Anti-Human PAI-1 Antibody

As a member of the Serpin superfamily of serine protease inhibitors, Serpin E1/PAI1 is the principal inhibitor of urokinase-type plasminogen activator (uPA) and tissue type plasminogen activator (tPA). As important regulators of extracellular matrix remodeling, uPA and PAI 1 play a major role in many processes such as angiogenesis, tumor invasion and obesity. For example, uPA and PAI1 are the only tumor prognostic factors validated at the highest level of evidence with regard to their clinical utility in breast cancer. The human PAI1 is initially synthesized as 402 amino acid precursor with a Nterminal signal peptide. PAI 1 may exist in one of two possible conformations, designated as active or latent.

518.55 €

MBS4159485-01mg

Anti-Human PAI-1 Antibody

994.62 €

MBS4159485-5x01mg

Anti-Human PAI-1 Antibody

3512.75 €

APOE11-S

Goat Anti-Human ApoE protein antiserum #1

1007.6 €

VGLUT21-S

Rabbit Anti-Human VGLUT2/DNPI antiserum #1

1007.6 €

C3D11-S

Sheep Anti-Human C3d antiserum

1007.6 €