Catalog number: 10006 - YF-MA17574
Product Category: Business & Industrial > Science & Laboratory
Size: 100 ug
APR14857G
A Monoclonal antibody against Human ADRM1 (clone 3D11). The antibodies are raised in Mouse and are from clone 3D11. This antibody is applicable in WB and IHC-P, E
APR14859G
A Monoclonal antibody against Human ADRM1 (monoclonal) (M02). The antibodies are raised in Mouse and are from clone 3D11. This antibody is applicable in WB, E
8119-01mg
The adhesion-regulating molecule 1 (ADRM1) is thought to be involved in protein recruitment and cell adhesion and functions as a proteasomal ubiquitin receptor (1). ADRM1 promotes the activity of UCH-L5 and plays a role in lymphocyte homing. The carboxy-terminal domain of mammalian ADRM1 serves to bind and enhance the isopeptidase activity of UCHL5/UCH37, perhaps serving as a mechanism to accelerate ubiquitin chain disassembly (2,3). ADRM1 expression is induced by IFN-gamma in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis (4,5).