ADGRL3 ELISA Kit (Human) (OKCD00795)
1598.43 €
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Catalog number: 247 - OKCD00795
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 96 Wells
OKCD00795
ADGRL3 ELISA Kit (Human) (OKCD00795)
Description of target: Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells (PubMed:26235030). Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex.By similarity
 <p>Manually curated information which has been propagated from a related experimentally characterized protein.</p>
 
 
 <p><a href="/manual/evidences#ECO:0000250">More…</a></p> Manual assertion inferred from sequence similarity toiUniProtKB:Q80TS3 (AGRL3_MOUSE)1 Publication
 <p>Manually curated information which has been inferred by a curator based on his/her scientific knowledge or on the scientific content of an article.</p>
 
 
 <p><a href="/manual/evidences#ECO:0000305">More…</a></p> Manual assertion inferred by curator fromiRef.5"Structural basis of latrophilin-FLRT-UNC5 interaction in cell adhesion."_x005F_x005F_x000D_Lu Y.C., Nazarko O.V., Sando R. III, Salzman G.S., Suedhof T.C., Arac D._x005F_x005F_x000D_Structure 23:1678-1691(2015) [PubMed] [Europe PMC] [Abstract]Cited for: X-RAY CRYSTALLOGRAPHY (3.60 ANGSTROMS) OF 132-392 IN COMPLEX WITH FLRT3 AND CALCIUM IONS, INTERACTION WITH FLRT3, IDENTIFICATION IN COMPLEXES WITH FLTR3; UNC5B AND UNC5D, DISULFIDE BOND, FUNCTION, SUBCELLULAR LOCATION, MUTAGENESIS OF 249-TYR--THR-252 AND ARG-308, REGION. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.114 ng/mL
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