ADCP Bioassay Effector Cell FcγRIIa (H variant) /NFAT Reporter-Jurkat
10567.13 €
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Catalog number: 421 - 71273
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 2 vials
60538
TIGIT / NFAT Reporter - Jurkat Cell Line
Recombinant Jurkat cell line constitutively expressing a full length human TIGIT (T_x000D_cell Immunoreceptor with Immunoglobulin and ITIM domain; VSTM3), and a firefly luciferase_x000D_gene under the control of nuclear factor of activator T cells (NFAT) response element. Both_x000D_TIGIT and NFAT constructs have been stably integrated into Jurkat cells. TIGIT expression has_x000D_been confirmed by Western Blot, and TIGIT-specific NFAT response has been validated using a_x000D_TIGIT ligand, CD155 (PVR).
16596.83 €
60621
NFAT Reporter (Luc) - Jurkat Cell Line
The NFAT Reporter - Jurkat Cell Line contains a firefly luciferase gene under the control of the_x000D_NFAT response element stably integrated into Jurkat cells. This cell line has been validated for_x000D_response to thapsigargin, ionomycin, and phorbol 12-myristate 13-acetate (PMA). It is useful as_x000D_a control cell line for other NFAT reporter cell lines expressing various immune checkpoint_x000D_receptors.
3628.43 €
78323
TMIGD2/NFAT Luciferase Reporter Jurkat Cell Line
Recombinant Jurkat cell line expressing firefly luciferase under the control of an NFAT response element, and with constitutive expression of human TMIGD2 (Transmembrane and immunoglobulin domain containing 2; CD28H; NM_144615). Expression of the firefly luciferase gene is driven by NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway in these cells can be monitored by measuring luciferase activity.
15816.60 €
79853
Anti-CD19 CAR / NFAT (Luciferase) Reporter Jurkat Cell Line (CD19 SCFV-CD28-4-1BB-CD3ζ)
Anti-CD19 CAR/NFAT-luciferase reporter Jurkat cell line is a double stable cell line expressing anti-CD19 CAR and NFAT-luciferase reporter. It is made from the anti-CD19 CAR lentivirus (BPS Bioscience #79851). The reporter cell line has been validated for anti CD19-CAR expression by FACS, and for luciferase reporter activation stimulated by target cells including CD19/CHO recombinant cell line can be used for primary screening and functional validation of anti-CD19 CAR construct and lentivirus before testing in primary T cells.<br /><br />Anti-CD19 CAR consists of anti-CD19 scFv linked to 3rd generation CAR (Chimeric Antigen Receptor) containing CD28, 4-1BB co-stimulatory domains, and CD3ζ signaling domain.<br />
15816.60 €
ABC-RC101D
Woodchuck PD-1/NFAT Report Cell Line-Jurkat
Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of woodchuck (groundhog, Marmota monax) PD-1 (Programmed Cell Death 1, PDCD1, SLEB2, CD279, GenBank Accession #HQ403652).
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