Activin-A Activin A Human Recombinant Protein, Plant
530.25 €
In Stock
quantity
product details
Catalog number: 519 - PROTP08476
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: Regular: 10ug
PROTP08476
Activin-A Activin A Human Recombinant Protein, Plant
Activin A human Recombinant produced in Nicotiana benthamiana plant is a disulfide-linked homodimers of two betaA chains, each containing 116 amino residues (molecular formula C<SUB>600</SUB>H<SUB>911</SUB>N<SUB>173</SUB>O<SUB>174</SUB>S<SUB>13</SUB>) and 6-His-tag at the N-terminal having the total molecular mass of 27.4kDa.
530.25 €
40-643
Activin A Recombinant Protein
Activin A is a TGF-β family member that exhibits a wide range of biological activities, including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Activin A binds to the two forms of activin receptor type I (Act RI-A and Act RI-B) and two forms of activin receptor type II (Act RII-A and Act RII-B). Activins are homodimers or heterodimers of different β subunits. They are produced as precursor proteins with an amino terminal propeptide that is cleaved to release the C-terminal bioactive ligand. Recombinant Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.
602.62 €