ABT-888 (Veliparib)
385.62 €
385.62 €
In Stock
quantity
product details
Catalog number: 607 - A3002-10
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 10 mg
27101
ABT-888 (Veliparib)
ABT-888 (Veliparib) is a potent inhibitor of both PARP-1 and PARP-2. In the MX-1 breast xenograft model (BRCA1 deletion and BRCA2 mutation), ABT-888 potentiated cisplatin, carboplatin, and cyclophosphamide, causing regression of established tumors, whereas with comparable doses of cytotoxic agents alone, only modest tumor inhibition was exhibited.
575.70 €
Chromatin/Epigenetics|PARP#DNA Damage/DNA Repair|PARP