D493555

3,20-Disemicarbazone-11Beta,17,21-trihydroxy-pregna-1,4-diene-3,20-dione 21-Acetate

96580-08-4

595.39 €

D493565

3,20-Disemicarbazone-11beta,17,21-trihydroxy-pregna-1,4-diene-3,20-dione

97830-94-9

1969.50 €

D493545

3,20-Disemicarbazone-17,21-dihydroxy-pregna-1,4-diene-3,11,20-trione 21-Acetate

115097-56-8

378.75 €

B1164-25

Y-320

1220.48 €

B1164-5

Y-320

487.83 €

HY-15898

Y-320

Y-320 is a potent, orally active phenylpyrazoleanilide immunomodulator. Y-320 inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM. Y-320 enhances TP53, DMD, and COL17A1 PTC readthrough by G418 and increases cellular protein levels and protein synthesis. Y-320 concomitants use of with a low dose of Paclitaxel (HY-B0015) significantly sensitized multidrug resistance (MDR) tumors by inducing G2/M phase arrest and apoptosis. Y-320 can be used for research of rheumatoid arthritis (RA) and cancer[1][2][2].

801.52 €