3’-Azido-3’-deoxy-5-methoxyuridine
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Catalog number: 931 - TNU0196-10mg
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 10mg
HY-152713
3’-Azido-3’-deoxy-5-methoxyuridine
3’-Azido-3’-deoxy-5-methoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3’-Azido-3’-deoxy-5-methoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
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3’-Azido-3’-deoxy-5-methoxyuridine