GBLD 345 is a potent agonist of benzodiazepine receptor. Benzodiazepine receptor is an allosteric modulatory site on GABAA receptor [1]. The GABAA receptor is a ligand-gated ion channel and activated by ?-aminobutyric acid (GABA).
GBLD 345 is a potent agonist of benzodiazepine receptor. Benzodiazepine receptor is an allosteric modulatory site on GABAA receptor [1]. The GABAA receptor is a ligand-gated ion channel and activated by ?-aminobutyric acid (GABA).
WEHI-345 is a potent and selective RIPK2 kinase inhibitor with an IC50 of 0.13 μM, which delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation[1].