TMPRSS2 Lentivirus
6203.93 €
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Catalog number: 421 - 78011-3
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 500 µl x 2
78011-1
TMPRSS2 Lentivirus
Human transmembrane serine protease 2 (TMPRSS2) is an enzyme primarily expressed by endothelial cells across the respiratory and digestive tracts. It is involved in viral entry and spread of coronaviruses including SARS-CoV-2, the virus that causes COVID19. TMPRSS2 primes the spike protein by cleaving at the S1/S2 site, leading to the virus fusing to the respiratory epithelia on the cell surface through binding to ACE2. Blocking TMPRSS2 activity could potentially be an effective clinical therapy for COVID-19._x000D_<br />The TMPRSS2 Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an TMPRSS2 gene (NM_005656.4) driven by an EF1a promoter._x000D_
1355.92 €
78011-2
TMPRSS2 Lentivirus
Human transmembrane serine protease 2 (TMPRSS2) is an enzyme primarily expressed by endothelial cells across the respiratory and digestive tracts. It is involved in viral entry and spread of coronaviruses including SARS-CoV-2, the virus that causes COVID19. TMPRSS2 primes the spike protein by cleaving at the S1/S2 site, leading to the virus fusing to the respiratory epithelia on the cell surface through binding to ACE2. Blocking TMPRSS2 activity could potentially be an effective clinical therapy for COVID-19._x000D_<br />The TMPRSS2 Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an TMPRSS2 gene (NM_005656.4) driven by an EF1a promoter._x000D_
4666.20 €
78347-P
RFP Lentivirus
TurboRFP is a red (orange) fluorescent protein derived from sea anemone Entacmaea quadricolor. The RFP Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to infect almost all types mammalian cells, including primary and non-dividing cells. These viruses constitutively express TurboRFP under a CMV promoter. RFP expression and transduction efficiency can easily be verified and optimized via fluorescence microscopy or flow cytometry. RFP has an excitation wavelength of 553 nm, an emission wavelength of 574 nm, and an extinction coefficient of 92,000 M<sup>-1</sup>cm<sup>-1</sup>.
1355.92 €
The TMPRSS2 Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an TMPRSS2 gene (NM_005656.4) driven by an EF1a promoter._x000D_