(S,R,S)-AHPC-Me
401.75 €
401.75 €
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Catalog number: 544 - MBS5786099-25mg
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 25mg
HY-112078
(S,R,S)-AHPC-Me
(S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein[1]. (S,R,S)-AHPC-Me can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader. ARV-771 potently degrades BET protein in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM[2].
240.33 €