MBS4165816-01mL

Anti-Siglec-15 Antibody

873.5 €

MBS4165816-5x01mL

Anti-Siglec-15 Antibody

2964.5 €

E24CHB094

Anti-Siglec-15 / CD33L3 Reference Antibody (Medimmune anti-Siglec-15)

Available in various conjugation types.

487.5 €

101-M634

Anti-Human Siglec-9 Antibody

Siglecs are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal, Ig-like V-type domain that mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains (2 to 17), a single transmembrane region, and a cytoplasmic tail. The siglecs can be broadly classified into two subgroups: siglecs-1, -2, and -4, and a siglec-3/CD33-related subgroup (siglecs-3, and -5 through -13 in primates) defined by sequence similarity and clustered gene localization. They are widely expressed on hematopoietic cells, often in a cell-type-specific manner, and siglec-4/MAG is a myelin component in Schwann cells and oligodendrocytes. Their ligands, sialic acids, are negatively charged monosaccharides found on cell-surface glycoproteins and glycolipids. Although siglec functions continue to be defined, most have intracellular immunoreceptor tyrosine-based inhibitory motifs (ITIM), implicating them in the suppression of immunoreceptor signaling. They may also participate in cell/cell interactions or act as receptors for the entry of viral or bacterial pathogens.

748.5 €

DL98362A-100ul

Rabbit anti-Siglec 12 Antibody

SIGLECL1; SLG; Sialic acid-binding Ig-like lectin 12; Siglec-12; Sialic acid-binding Ig-like lectin-like 1; Siglec-L1

583.5 €

DL98362A-50ul

Rabbit anti-Siglec 12 Antibody

SIGLECL1; SLG; Sialic acid-binding Ig-like lectin 12; Siglec-12; Sialic acid-binding Ig-like lectin-like 1; Siglec-L1

453.45 €