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SARS-CoV-2 (COVID-19) Nucleocapsid Recombinant protein

SARS-CoV-2 (COVID-19) Nucleocapsid Recombinant protein
SARS-CoV-2 (COVID-19) Nucleocapsid Recombinant protein

SARS-CoV-2 (COVID-19) Nucleocapsid Recombinant protein

974.85 €

974.85 €
In Stock
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Catalog number: 223 - 39-113

Product Category: Business & Industrial > Science & Laboratory

Supplier:

ProSciGentaur

Size: 0.05 mg

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SARS-CoV-2 (COVID-19) Nucleocapsid Recombinant Protein

Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

1681.14 €

A human infecting coronavirus (viral pneumonia) called 2019 novel coronavirus, 2019-nCoV was found in the fish market at the city of Wuhan, Hubei province of China on December 2019. The 2019-nCoV shares an 87% identity to the 2 bat-derived severe acute respiratory syndrome 2018 SARS-CoV-2 located in Zhoushan of eastern China. 2019-nCoV has an analogous receptor-BD-structure to that of 2018 SARS-CoV, even though there is a.a. diversity so thus the 2019-nCoV might bind to ACE2 receptor protein (angiotensin-converting enzyme 2)  in humans. While bats are possibly the host of 2019-nCoV, researchers suspect that animal from the ocean sold at the seafood market was an intermediate host. RSCU analysis proposes that the 2019-nCoV is a recombinant within the viral spike glycoprotein between the bat coronavirus and an unknown coronavirus.