Catalog number: 544 - MBS8124218-5x96Tests
Product Category: Business & Industrial > Science & Laboratory
Size: 5x96Tests
RAS-A021
It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
RAS-T062
As of Nov 29th, confirmed cases of a new variant of concern (VOC) B.1.1.529 have been reported in South Africa, Botswana and more than 12 other countries. Thanks to the rapid sequencing efforts of South African scientists, the whole world is now alerted about this potentially devastating lineage, which was assigned the name Omicron by WHO.Omicron is a highly divergent variant with a high number of mutations (26-35) in the spike. Identification of some familiar mutations that also appeared on other VOCs gives rises to concerns of its immune escape potential and higher transmissibility. To facilitate the mutant-related research, drug trials and vaccine development, a high-throughput assay to measure IgG antibodies against the mutants is in urgent need.
RAS-T134
According to the data from GISAID, until 25th July, BA.5 was accounted for 52% of the sequence library, making it the dominant strain in a new global outbreak. Some research results showed that BA.5 seems to be the most infectious version of SARS-CoV-2 with the R0 value of 18.6 (about 2.79 in wild type). Furthermore, the strong immune escape ability is also a powerful blessing for BA.5 to quickly become the dominant strain. A report from New York showed that the breakthrough infection capacity of BA.5 should be 4.2 times of BA.1. The latest research shows that BA.5 has also a strong immune escape from the serum of BA.1 infected people, which means that the existing "immune wall" in the population may be ineffective against BA.5.To facilitate the mutant-related research, drug trials and vaccine development in clinical reasearch, a high-throughput assay to measure IgG antibodies against the mutants is in urgent need.
RAS-T136
Since December 2019, the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated disease, COVID-19, has caused a devastating pandemic worldwide.As the virus spreads globally, the continuous emergence of new mutant strains escalated the challenge on humans.To facilitate the mutant-related research, drug trials and vaccine development, a high-throughput assay to measure IgG antibodies against the mutants is in urgent need.