S1PR1 agonist 1
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Catalog number: 804 - HY-143864
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
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HY-149763
Aβ42 agonist-1
Aβ42 agonist-1 (compound 7a) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-1 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-1 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells[1].
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HY-149803
S1R agonist 1
S1R agonist 1 (Compound 6b) is a selective S1R agonist with Kis of 0.93 nM and 72 nM for S1R and S2R, respectively. S1R agonist 1 exhibits neuroprotection against ROS and NMDA-induced neurotoxicity[1].
459.17 €
HY-149807
TGR5 agonist 1
TGR5 agonist 1 (compound 18) is a potent TGR5 agonist with an EC50 value of 0.31 µM[1].
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S1PR1 agonist 1 is a potent agonist of S1PR1. Sphingosine-1-phosphate (S1P) is a cell membrane-derived lysophospholipid signalling molecule that exerts its physiological functions mainly by stimulating some members of the G protein-coupled receptor family. S1PR1 agonist 1 has the potential for the research of autoimmune diseases (extracted from patent WO2021175223A1, compound 22)[1].