Recombinant Human BD-4

MBS286194-01mg

RecombinantHumanBeta-2-microglobulin(B2M)protein

797 €

MBS286194-05mg

RecombinantHumanBeta-2-microglobulin(B2M)protein

1874.38 €

MBS286194-1mg

RecombinantHumanBeta-2-microglobulin(B2M)protein

2524.62 €

CD00141-5ug

Recombinant Rat BD-4 protein

Defensins (alpha and beta) are cationic peptides with antimicrobial activity against Gram-negative and Gram-positive bacteria, fungi, and enveloped viruses. They are 2-6 kDa proteins and take important roles in innate immune system. On the basis of their size and pattern of disulfide bonding, mammalian defensins are classified into alpha, beta and theta categories. β-Defensins are expressed on some leukocytes and at epithelial surfaces. They contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Because β-defensins are cationic peptides, they can therefore interact with the membrane of invading microbes, which are negative due to lipopolysaccharides (LPS) and lipoteichoic acid (LTA) found in the cell membrane. Especially, they have higher affinity to the binding site compared to Ca2+ and Mg2+ ions. Furthermore, they can affect the stability of the membrane. Additionally, they are not only have the ability to strengthen the innate immune system but can also enhance the adaptive immune system by chemotaxis of monocytes, T-lymphocytes, dendritic cells and mast cells to the infection site.

418.4 €

PROTQ8WTQ1

BD-4 Beta Defensin-4 Human Recombinant Protein

Beta Defensin-4 Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 50 amino acids and having a molecular mass of 6 kDa. The BD-4 is purified by proprietary chromatographic techniques.

525 €

4372-1000

BD-2, human recombinant

7090.8 €