Rat Anti-Mouse LPAM-1-LE/AF
753.46 €
753.46 €
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product details
Catalog number: 544 - MBS673625-05mg
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 0.5mg
103-M176
Anti-Mouse LPAM-1 Antibody
The antibody is specific for a combinatorial determinate of integrin α4β7complex. Integrin α4β7 is composed of a 150 kD (α4 or CD49d) and a 130 kD (β7) heterodimer, also known as CD49d/β7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin α4β7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues.
755.99 €