PT 1
613.47 €
613.47 €
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Catalog number: 607 - B7572-10
Product Category: Business & Industrial > Science & Laboratory
Supplier:
Gentaur
Size: 10 mg
ABC-TC214S
B104-1-1
Tissue: embryo; Transfected with EcoR1 digested DNA from the rat neuroblastoma B104; Original line: NIH/3T3. The cells contain the transforming gene neu which induces synthesis of a tumor antigen of relative molecular mass 185, 000 (p185), strongly associated with the presence of neuro/glioblastoma oncogenes. The neu oncogene bears homology to erb-B and the tumor antigen p185 is serologically related to the epidermal growth factor receptor.
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PT 1 is a selective activator of AMPK with EC50 value of 0.3 ?M for AMPK ?1?1?1 [1]. AMP-activated protein kinase (AMPK) is serine/threonine protein kinase that involved in cellular energy homeostasis and acts as an energy sensor.