Catalog number: 821 - AJ844-70211-0
Product Category: Business & Industrial > Science & Laboratory
Size: each
3091-002mg
AID Antibody: Activation-induced cytidine deaminase (AID) was initially discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that showed cytidine deaminase properties in stimulated B cell lines. It is necessary for somatic hypermutation and class switch recombination in B cells, but inappropriate or dysregulated expression AID is often found in tumors and B cell neoplasms. Although it is structurally and functionally similar to the APOBEC proteins, it appears unlikely that AID deaminates dC to dU residues in HIV cDNA as does APOBEC3G.
BT-AP00304-100ul
AICDA encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. Activation-induced cytidine deaminase is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
BT-AP00304-20ul
AICDA encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. Activation-induced cytidine deaminase is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).