PDK1 (Phospho-Ser241) Antibody
371.18 €
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Catalog number: 426 - E011005-1
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 50μg/50μl
BT-AP07524-20ul
PDK1(Phospho Ser241) Polyclonal Antibody
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.|Phosphorylates and activates not only PKB/AKT| but also PKA| PKC-zeta| RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.|PTM:Phosphorylated on tyrosine and serine/threonine. Phosphorylation on Ser-241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser-241| leading to its own activation.|Belongs to the protein kinase superfamily.|Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDK1 subfamily.|Contains 1 PH domain.|Contains 1 protein kinase domain.|subcellular location:Membrane-associated after cell stimulation leading to its translocation. Tyrosine phosphorylation seems to occur only at the plasma membrane.|subunit:Interacts with TUSC4.|tissue specificity:Appears to be expressed ubiquitously.|
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BT-AP07524-50ul
PDK1(Phospho Ser241) Polyclonal Antibody
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.|Phosphorylates and activates not only PKB/AKT| but also PKA| PKC-zeta| RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.|PTM:Phosphorylated on tyrosine and serine/threonine. Phosphorylation on Ser-241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser-241| leading to its own activation.|Belongs to the protein kinase superfamily.|Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDK1 subfamily.|Contains 1 PH domain.|Contains 1 protein kinase domain.|subcellular location:Membrane-associated after cell stimulation leading to its translocation. Tyrosine phosphorylation seems to occur only at the plasma membrane.|subunit:Interacts with TUSC4.|tissue specificity:Appears to be expressed ubiquitously.|
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BZ16287
Phospho-PDPK1 (Ser241) polyclonal antibody
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.