Diluent buffer for the binding agent. Suitable for use with the PDE assay kit (BPS Bioscience, Cat. #60300) for the study of phosphodiesterases which can hydrolyze cAMP (PDEs 1, 2, 3, 4, 7, 8, 10, and 11). Not suitable with cGMP-selective PDEs (5, 6, 9).
Diluent buffer for the binding agent. Suitable for use with the PDE assay kit (BPS Bioscience, Cat. #60300) for the study of phosphodiesterases which can hydrolyze cGMP (PDEs 1, 2, 3, 5, 6, 9, 10, and 11). Not suitable with cAMP-selective PDEs (4, 7, 8).
Antioxidant agent-13 (Compound 5f) is an antioxidant agent. Antioxidant agent-13 inhibits DPPH and FRAP with IC50s of 80.33 and 85.69 μM. Antioxidant agent-13 also inhibits LOX and XO enzymes with IC50s of 16.85 and 23.01 μM[1].
Antiproliferative agent-32 (Compound 1c) inhibits the phosphorylation of PI3K/Akt/mTOR signaling pathway. Antiproliferative agent-32 inhibits Huh7 and SK-Hep-1 cells proliferation, and induce cells apoptosis, causes mitochondrial damage. Antiproliferative agent-32 can be used for research of hepatocellular carcinoma[1].
Antiproliferative agent-33 (Compound 2g) is an anti-proliferative, antifungal, and antibacterial agent. Antiproliferative agent-33 inhibits MDA-MB-231 cell proliferation (IC50: 16.38 μM). Antiproliferative agent-33 inhibits gram-negative bacteria growth, and inhibits S. faecalis with an MIC value of 8 μg/mL[1].
Extra binding agent for use with the PDE assay kit (BPS Bioscience, Cat. #60300) or related PDE assay kits for the study of phosphodiesterase activity.