p53 (Phospho-Ser9) Polyclonal Antibody
658.5 EUR
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Produktdetaljer
Katalognummer: 355 - 12214
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 100ul
BT-AP12675-100ul
p53(Phospho Ser9) Polyclonal Antibody
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).
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BT-AP09770-100ul
GSK3 beta(Phospho Ser9) Polyclonal Antibody
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.