p53 (Di Methyl Lys370) Polyclonal Antibody
480 EUR
480 EUR
In Stock
quantity
Produktdetaljer
Katalognummer: 965 - JOT-AP06806-100ul
Produktkategori: Företag och industri > Vetenskap och laboratorium
Leverantör:
Gentaur
Storlek: 100ul
Parameters
| Additional information | TP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains.Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of TP53 and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). |
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