OKBB00652-96W - PCSK9 ELISA Kit (Mouse)
964 EUR
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Katalognummer: 247 - OKBB00652-96W
Produktkategori: Företag och industri > Vetenskap och laboratorium
Gentaur
Storlek: 96Wells
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| Additional information | PCSK9 ELISA Kit (Mouse) |
|---|
OKBB00652
PCSK9 ELISA Kit (Mouse) (OKBB00652)
Description of target: Proprotein convertase subtilisin/kexin type 9, also known as PCSK9, is an enzyme that in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. By genomic sequence analysis, the PCSK9 gene was mapped to chromosome 1p32. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. Reduced LDLR levels result in decreased metabolism of low-density lipoproteins (LDL), which could lead to hypercholesterolemia. PCSK9 may also have a role in the differentiation of cortical neurons.;Species reactivity: Mouse;Application: ELISA;Assay info: <b>Assay Methodology: </b>Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL
1136.2 €
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