NT5E ELISA Kit (Human) (OKBB00978)

OKBB00978

NT5E ELISA Kit (Human) (OKBB00978)

Description of target: 5'-nucleotidase (5'-NT), also known as ecto-5'-nucleotidase or CD73 (Cluster of Differentiation 73), is an enzyme that in humans is encoded by the NT5E gene. Ecto-5-prime-nucleotidase catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. And the enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases. Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. Rareallelic variants are associated with a syndrome of adult-onset calcification of joints and arteries (CALJA) affecting the iliac, femoral, and tibial arteries reducing circulation in the legs and the joints of the hands and feet causing pain.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml

1066 €

OKBB00978-96W

OKBB00978-96W - NT5E ELISA Kit (Human)

944.5 €

ELA-E0104h

Human NT5E ELISA Kit

43183 €

RDR-NT5E-Hu-96Tests

Human 5'-Nucleotidase, Ecto (NT5E) ELISA Kit

181 €

SEB250Hu-10x96

Human 5'-Nucleotidase, Ecto (NT5E) ELISA Kit

Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human 5'-Nucleotidase, Ecto (NT5E) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species. This is a cost efficient bulk pack of 10 plates of 96 wells each, conveniently packed along with the other reagents in 10 separate kits to avoid unsealing the plates and reagents that won't be immediately used.

8518.4 €

SEB250Hu-10x96wellstestplate

Human 5'-Nucleotidase, Ecto (NT5E) ELISA Kit

This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human 5'-Nucleotidase, Ecto (NT5E) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

8427.38 €