Mouse Anti-Human Foxp3-FITC
2356.71 €
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Catalog number: 544 - MBS670444-5x100Tests
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 5x100Tests
DL22204F-50Tests
Anti-Human/Mouse/Rat Foxp3 Monoclonal Antibody(FITC Conjugated)
FOXP3 is a 50-55 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4+/CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in "scurfy" mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity. In human, unlike in mouse, two isoforms of FOXP3 have been reported: one (FOXP3) corresponding to the canonical full-length sequence; the other (FOXP3 δ2) lacking exon 2. The 150D monoclonal antibody reacts with human, mouse and rat FOXP3. The 150D antibody recognizes FOXP3 epitope encoded by exon 2.
696.90 €
CSB-PA15229C0Rb-100ug
FOXP3 Antibody, FITC conjugated
A polyclonal antibody against FOXP3. Recognizes FOXP3 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA
365.62 €
CSB-PA15229C0Rb-50ug
FOXP3 Antibody, FITC conjugated
A polyclonal antibody against FOXP3. Recognizes FOXP3 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA