Mouse anti-CD40 Antibody
465.00 €
In Stock
quantity
product details
Catalog number: 586 - DL99378A-50ul
Product Category: Business & Industrial > Science & Laboratory
Gentaur
Size: 50 ul
A00068-1
Anti-CD40/Cd40 Antibody Picoband™
Western blot, 0.1-0.5μg/ml;_x000D_Direct ELISA, 0.1-0.5μg/ml
381.00 €
ER1803-54
Anti-CD40 Antibody
Resting B cells can be activated and clonally expanded into antibody-producing cells in response to a combination of cell contact and soluble signals provided by primed helper T (Th) cells. A receptor ligand pair central to the trans-mission of this signal is CD40, expressed on the surface of B cells, together with CD40L, expressed on activated T cells. In the presence of such stimulus, IL-4 and IL-13 are capable of triggering immunoglobulin class switching and secretion of IgE. B cells are sensitive to these cytokines only subsequent to CD40/CD40L-driven DNA synthesis. A downstream mediator of the CD40 signaling pathway, designated CRAF, is a member of an expanding family of proteins that contain a conserved cysteine- and histidine-rich RING finger motif.
433.50 €