Catalog number: 544 - MBS8510199-01mLAF610
Product Category: Business & Industrial > Science & Laboratory
Size: 0.1mL(AF610)
ABP50357-01ml
A polyclonal antibody for detection of MEK-2 phospho Thr394) from Human, Mouse, Rat. This MEK-2 phospho Thr394) antibody is for WB, IHC-P, IP, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human MEK-2 around the phosphorylation site of T394
ABP50357-02ml
A polyclonal antibody for detection of MEK-2 phospho Thr394) from Human, Mouse, Rat. This MEK-2 phospho Thr394) antibody is for WB, IHC-P, IP, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human MEK-2 around the phosphorylation site of T394
BT-AP11253-100ul
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.