GWB-PSC83D

JAK pathway ISRE reporter cell line

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60406

SRE Reporter - HEK293 Cell Line (ERK Pathway)

The SRE Reporter - HEK293 cell line is designed for monitoring the activity of the JAK/STAT signaling pathway. The SRE Reporter - HEK293 cell line contains a firefly luciferase gene under the control of SRE responsive elements stably integrated into HEK293 cells, resulting in an ERK pathway-responsive reporter cell line.

3946.57 €

GWB-PSFA8A

SRE Reporter - HEK293 Cell Line (ERK Pathway)

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GWB-PS8936

Gli Reporter - NIH3T3 Cell line (Hedgehog Pathway)

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78653

GAS Luciferase Reporter Lentivirus (IFN-γ/JAK/STAT1 Pathway)

The GAS Luciferase Reporter Lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to transduce almost all types of mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by three copies of the interferon gamma (IFN-γ) activated sites (GAS) located upstream of the minimal TATA promoter and a puromycin selection gene for the selection of stable clones. After transduction, the GAS-regulated gene expression in the target cells can be monitored by measuring the luciferase activity.

1416.53 €

79289

CD137/NF-κB Reporter - HEK293 Recombinant Cell Line

Recombinant HEK293 cell line expressing a full length human CD137 (NM_003811). The NF-κB luciferase reporter construct is stably integrated into the genome. The firefly luciferase gene is controlled by 4 copies of NF-κB response element located upstream of the TATA promoter. Following activation by human CD137 ligand, NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene.

16960.42 €