Catalog number: 544 - MBS153305-5x005mg
Product Category: Business & Industrial > Science & Laboratory
Size: 5x0.05mg
91-822
Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. They are typically divided among three IFN classes: Type I, Type II and Type III. IFNA4 is a secreted protein and produced by macrophages. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 .
95-110
The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains (reviewed in 1). Alpha 4 (4) chain associates with either beta 1 (1) or beta 77) chain. It has been demonstrated that the putative ligand-binding sites of both integrin 41 and 47 is located on the 4 chain. These ligands included Madcam, VCAM, and fibronectin (2-4). Madcam is known as the principal ligand for integrin a4b7. Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin 47, the gut mucosal homing receptor for peripheral T cells (5). This recombinant protein fragment includes the ligand and monoclonal antibody binding domains; this binding has been tested and verified in ELISA assays. This recombinant protein is recognized PSI antibodies Integrin 4 (IN1) (PSI 4827) and Integrin 4 (IN2) (PSI 4837), but not Integrin 4 (CT) (PSI 4783).
RPC223Hu02-1MG
This is Actinin Alpha 4 (ACTN4) recombinant protein for positive control, Immunogen, SDS-PAGE, WB.freeze-dried powderPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
RPC223Hu02-200ug
This is Actinin Alpha 4 (ACTN4) recombinant protein for positive control, Immunogen, SDS-PAGE, WB.freeze-dried powderPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
RPC223Hu02-500ug
This is Actinin Alpha 4 (ACTN4) recombinant protein for positive control, Immunogen, SDS-PAGE, WB.freeze-dried powderPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.