Katalognummer: 223 - 40-671
Produktkategori: Företag och industri > Vetenskap och laboratorium
Storlek: 5 ug
91-303
Tumor Necrosis Factor Receptor Superfamily Member 21 (TNFRSF21) is a type I transmembrane receptor that includes four extracellular cysteine-rich motifs and a cytoplasmic death domain. DR6 is highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. DR6 may activate NF-kappa-B and JNK to promote apoptosis and T-cell differentiation. In addition, DR6 binds with N-APP, which is released by the deprivation of Trophic-factor. It triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). DR6 is also expressed on the tumor cell lines and can be induced by TNF- alpha.
APB815Mu02-5MG
This is Active Interleukin 6 Receptor (IL6R) recombinant protein for Cell culture, Activity Assays.freeze-dried powderPBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.